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Heat stimuli below, at, and above pain threshold (PT; stimulation interval: 30 – 40 seconds) are applied to the skin and the participant gives continuous pain ratings on a visual analogue scale.


tonic heat stimulation model

Definition contributed by Anonymous
dual sensitization has been asserted to measure the following CONCEPTS
No concepts assertions have been added.

Phenotypes associated with dual sensitization


No associations have been added.


No associations have been added.


No associations have been added.

IMPLEMENTATIONS of dual sensitization
No implementations have been added.
EXTERNAL DATASETS for dual sensitization
No implementations have been added.

Experimental conditions are the subsets of an experiment that define the relevant experimental manipulation.


In the Cognitive Atlas, we define a contrast as any function over experimental conditions. The simplest contrast is the indicator value for a specific condition; more complex contrasts include linear or nonlinear functions of the indicator across different experimental conditions.

o Continuous ratings on a visual analogue scale
o Difference between initial sensation of temperature and sensation at the end of the stimulation

An indicator is a specific quantitative or qualitative variable that is recorded for analysis. These may include behavioral variables (such as response time, accuracy, or other measures of performance) or physiological variables (including genetics, psychophysiology, or brain imaging data).


Evaluation of a diagnostic tonic heat pain fMRI procedure with continuous rating of pain perception at four randomized stimulus intensities
Kleinböhl D, Amann M, Baudendistel K, Hölzl R, Schad L
Neuroimage, 16:6 Special Issue (ISSN 1053-8119)

Psychophysical measures of sensitization to tonic heat discriminate chronic pain patients.
Kleinböhl D, Hölzl R, Möltner A, Rommel C, Weber C, Osswald PM
1999 May